⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976364 | 1.00 | — | — | |
| SCHEMBL9035200 | 1.00 | — | — | |
| SCHEMBL9184177 | 0.79 | — | — | |
| SCHEMBL9661583 | 0.79 | — | — | |
| SCHEMBL289406 | 0.75 | CRBN (0.41) | — | |
| SCHEMBL4905898 | 0.74 | CREBBP (1.00) | — | |
| SCHEMBL14258530 | 0.74 | CREBBP (1.00) | — | |
| SCHEMBL4907033 | 0.74 | CREBBP (1.00) | — | |
| SCHEMBL16611889 | 0.74 | — | — | |
| SCHEMBL5768296 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420628-B2 | Substituted beta-lactams | ALLERGAN, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420628-B2 | Substituted beta-lactams | ALLERGAN, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8202855-B2 | Substituted beta-lactams | ALLERGAN, INC (US) | 2012-06-19 | — | — | US | disclosed |
| US-8202855-B2 | Substituted beta-lactams | ALLERGAN, INC (US) | 2012-06-19 | — | — | US | disclosed |
| EP-1877050-B1 | SUBSTITUTED BETA-LACTAMS AND THEIR USE IN MEDICINE | ALLERGAN INC (US) | 2011-07-06 | — | — | EP | disclosed |
| US-7772392-B2 | Therapeutic substituted β-lactams | ALLERGAN, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7772392-B2 | Therapeutic substituted β-lactams | ALLERGAN, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090318404-A1 | SUBSTITUTED BETA-LACTAMS | ALLERGAN INC. (US) | 2009-12-24 | — | — | US | disclosed |
| US-20090318404-A1 | SUBSTITUTED BETA-LACTAMS | ALLERGAN INC. (US) | 2009-12-24 | — | — | US | disclosed |
| WO-2009111417-A1 | SUBSTITUTED BETA-LACTAMS | ALLERGAN, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| US-20090227557-A1 | SUBSTITUTED BETA-LACTAMS | ALLERGAN, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227557-A1 | SUBSTITUTED BETA-LACTAMS | ALLERGAN, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |