Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethohexadiol SCHEMBL38007 | 0.97 | LMNA (1.00) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL6282991 | 0.97 | LMNA (1.00) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL10731659 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL11502837 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL1110807 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL29399150 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL28358701 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL610774 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL20787860 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 | |
| Ethohexadiol SCHEMBL27982443 | 0.95 | LMNA (0.95) | LMNATSHRALDH1A1CYP2D6SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341759-A2 | 3-SUBSTITUTED OXINDOLE BETA 3 AGONISTS | ELI LILLY AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002038544-A2 | 3-SUBSTITUTED OXINDOLE BETA 3 AGONISTS | ELI LILLY AND COMPANY (US) | 2002-05-16 | — | — | WO | disclosed |