Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 10/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981295 | 0.79 | TLR8 (0.47) | GNRHR | |
| SCHEMBL6976619 | 0.75 | TLR8 (0.43) | GNRHR | |
| SCHEMBL7905321 | 0.73 | GNRHR (0.65) | GNRHR | |
| SCHEMBL6980604 | 0.72 | GNRHR (0.82) | GNRHR | |
| SCHEMBL6981337 | 0.72 | GNRHR (1.00) | GNRHR | |
| SCHEMBL8695570 | 0.72 | KDM4E (0.45) | — | |
| Hydrochloric Acid SCHEMBL6983627 | 0.71 | GNRHR (0.99) | GNRHR | |
| SCHEMBL6983848 | 0.71 | GNRHR (0.57) | GNRHR | |
| SCHEMBL6983847 | 0.70 | GNRHR (0.60) | GNRHR | |
| SCHEMBL8697376 | 0.70 | GNRHR (0.88) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095038-B1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-0873336-B1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6200957-B1 | USEFUL FOR TREATMENT OF VARIETY OF SEX-HORMONE RELATED AND OTHER CONDITIONS IN BOTH MEN AND WOMEN | MERCK & CO., INC. | 2001-03-13 | — | — | US | disclosed |