SCHEMBL6977021

SCHEMBL6977021

[CH2]NCC1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396976 0.97
SCHEMBL3534488 0.94
SCHEMBL273580 0.87
SCHEMBL1488097 0.75
SCHEMBL1679662 0.73 ADH1B (0.55)
SCHEMBL18225062 0.73
SCHEMBL25047164 0.71 ADH1B (0.59)
SCHEMBL1679009 0.71 ADH1B (0.52)
SCHEMBL1679033 0.71 ADH1B (0.59)
SCHEMBL18849498 0.71 ADH1B (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160145242-A1 PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC. NIPPON SODA CO., LTD. (JP) 2016-05-26 US disclosed
EP-2998298-A1 PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC. Nippon Soda Co., Ltd. (JP) 2016-03-23 EP disclosed
EP-0870765-B1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARM CO LTD (JP) 2003-11-19 EP disclosed
US-5981557-A HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0870765-A1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed
US-5569665-A Peptidyl derivatives and their use as metalloproteinases inhibitors CELLTECH LIMITED (GB) 1996-10-29 US disclosed
US-5530128-A ENZYME INHIBITOR AS ANTITUMOR AGENT CELLTECH THERAPEUTICS LIMITED (GB) 1996-06-25 US disclosed
EP-0489577-B1 Peptidyl derivatives CELLTECH LTD (GB) 1995-03-22 EP disclosed
EP-0605682-A1 PEPTIDYL DERIVATIVES AND THEIR USE AS METALLOPROTEINASES INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1994-07-13 EP disclosed
EP-0605681-A1 SULPHAMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1994-07-13 EP disclosed
US-5300501-A Metalloproteinase inhibitors CELLTECH LIMITED (GB) 1994-04-05 US disclosed
WO-1993024475-A1 SULPHAMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS CELLTECH LIMITED (GB) 1993-12-09 WO disclosed
WO-1993024449-A1 PEPTIDYL DERIVATIVES AND THEIR USE AS METALLOPROTEINASES INHIBITORS CELLTECH LIMITED (GB) 1993-12-09 WO disclosed
WO-1992009565-A1 PEPTIDYL DERIVATIVES CELLTECH LIMITED (GB) 1992-06-11 WO disclosed
EP-0489577-A1 Peptidyl derivatives CELLTECH LIMITED (GB) 1992-06-10 EP disclosed