Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977207 | 0.97 | LTB4R (0.55) | LTB4RNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6759706 | 0.97 | LTB4R (0.62) | LTB4RNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6760787 | 0.92 | LTB4R (0.65) | LTB4RNPC1RAB9APAX8KLF5 | |
| SCHEMBL6759707 | 0.88 | LTB4R (0.49) | LTB4RNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6760792 | 0.83 | LTB4R (0.52) | LTB4RNPC1RAB9AMAPTMAPK1 | |
| SCHEMBL6762408 | 0.82 | LTB4R (0.75) | LTB4RADORA3ADORA2AADORA1 | |
| SCHEMBL6757593 | 0.79 | LTB4R (0.47) | LTB4RHSD17B10ADORA3ADORA2AADORA1 | |
| SCHEMBL6759615 | 0.78 | LTB4R (0.67) | LTB4RADORA1 | |
| SCHEMBL6755910 | 0.75 | LTB4R (0.62) | LTB4RADORA1 | |
| SCHEMBL6757553 | 0.75 | LTB4R (1.00) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999856-B1 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-05-14 | — | — | EP | disclosed |