Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976964 | 0.78 | F2 (0.48) | PRSS1F2PRSS2PRSS3PLAU | |
| SCHEMBL7062388 | 0.75 | F10 (0.58) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7121498 | 0.75 | F10 (0.49) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL6981412 | 0.74 | PTPN1 (0.53) | PRSS1F2PRSS2PRSS3PLAU | |
| SCHEMBL6967577 | 0.74 | F2 (0.44) | PRSS1F2PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL8119814 | 0.73 | F10 (0.46) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7088555 | 0.72 | HDAC1 (0.51) | PRSS1PRSS2PRSS3PLAUF10 | |
| SCHEMBL8114685 | 0.72 | F2 (0.52) | PRSS1F2PRSS2PRSS3PLAU | |
| SCHEMBL9071660 | 0.70 | OPRM1 (0.46) | OPRM1OPRD1 | |
| SCHEMBL1624321 | 0.69 | F10 (0.51) | PRSS1F2PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284961-A1 | GLYCINAMIDES | MERCK PATENT GmbH (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092219-A1 | GLYCINAMIDES | MERCK PATENT GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |