Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 18/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983386 | 0.89 | SCD (0.49) | SCD | |
| SCHEMBL6983361 | 0.86 | SCD (0.48) | SCD | |
| SCHEMBL6981269 | 0.83 | SCD (0.52) | SCDEPHX2 | |
| Hydrochloric Acid SCHEMBL6983385 | 0.80 | SIGLEC9 (0.40) | SCDKDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL6988459 | 0.77 | MAPK14 (0.41) | KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL6984405 | 0.77 | SCD (0.50) | SCDEPHX2 | |
| SCHEMBL6346040 | 0.76 | KDM4E (0.43) | KDM4EPOLBMAPK1SMN1; SMN2EPHX2 | |
| SCHEMBL6347242 | 0.76 | KDM4E (0.43) | KDM4EPOLBMAPK1SMN1; SMN2EPHX2 | |
| SCHEMBL6982506 | 0.75 | SCD (0.47) | SCDEPHX2 | |
| SCHEMBL6982128 | 0.75 | SCD (0.42) | SCDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |