Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6985678 | 0.99 | SCD (0.42) | SCDEPHX2CYP2C9CYP2J2MAPT | |
| SCHEMBL6987898 | 0.88 | MAPK14 (0.38) | SCD | |
| SCHEMBL6983386 | 0.86 | SCD (0.49) | SCDMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6985436 | 0.85 | SCD (0.38) | SCDEPHX2CYP2C9CYP2J2MAPT | |
| Hydrochloric Acid SCHEMBL6980263 | 0.84 | MAPT (0.46) | SCDEPHX2CYP2C9CYP2J2MAPT | |
| SCHEMBL6988687 | 0.83 | LMNA (0.45) | — | |
| SCHEMBL6982897 | 0.82 | KDM4E (0.42) | SCD | |
| SCHEMBL6986945 | 0.79 | F10 (0.53) | MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6985167 | 0.79 | F10 (0.53) | MAPTL3MBTL1 | |
| SCHEMBL6985540 | 0.76 | MAPK14 (0.40) | SCDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |