Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158608 | 0.89 | HSD17B10 (0.35) | HSD17B10 | |
| SCHEMBL431029 | 0.86 | — | — | |
| SCHEMBL15966191 | 0.84 | ALDH1A1 (0.32) | — | |
| Ether SCHEMBL9988157 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL29938566 | 0.81 | HTT (0.43) | — | |
| SCHEMBL578959 | 0.80 | — | — | |
| SCHEMBL31381729 | 0.77 | — | — | |
| SCHEMBL28505598 | 0.77 | — | — | |
| SCHEMBL4348858 | 0.76 | HSD17B10 (0.41) | HSD17B10 | |
| SCHEMBL430949 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272488-A2 | TRI-ARYL-SUBSTITUTED-ETHANE PDE4 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001070738-A2 | TRI-ARYL-SUBSTITUTED-ETHANE PDE4 INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2001-09-27 | — | — | WO | disclosed |