Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.52 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.52 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.52 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713117 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2TAAR1ALDH1A1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7943506 | 0.93 | SMN1; SMN2 (0.51) | SMN1; SMN2TAAR1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL17152386 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2TAAR1ALDH1A1KMT2AGLA | |
| SCHEMBL27139985 | 0.85 | MTNR1A (0.54) | ALDH1A1KMT2ARAB9A | |
| SCHEMBL6962554 | 0.85 | MTNR1A (0.54) | ALDH1A1KMT2ARAB9A | |
| SCHEMBL13073347 | 0.84 | KMT2A (0.63) | SMN1; SMN2TAAR1ALDH1A1KMT2AFPR2 | |
| SCHEMBL7943508 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2TAAR1ALDH1A1KMT2AGLA | |
| SCHEMBL9221733 | 0.83 | MAPT (0.55) | SMN1; SMN2TAAR1ALDH1A1KMT2AGLA | |
| SCHEMBL11714142 | 0.83 | HDAC8 (0.55) | SMN1; SMN2NPC1GAARAB9APLAAT3 | |
| SCHEMBL24322367 | 0.83 | POLB (0.54) | ITGB3ITGA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |