Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.61 |
| ▸ | HTR1A | P08908 | 7/20 | 0.59 |
| ▸ | HTR1D | P28221 | 7/20 | 0.59 |
| ▸ | HTR1B | P28222 | 7/20 | 0.59 |
| ▸ | HTR7 | P34969 | 6/20 | 0.59 |
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.59 |
| ▸ | DRD3 | P35462 | 6/20 | 0.59 |
| ▸ | HTR2A | P28223 | 6/20 | 0.59 |
| ▸ | HTR2C | P28335 | 5/20 | 0.59 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.59 |
| ▸ | HTR2B | P41595 | 5/20 | 0.59 |
| ▸ | HTR1E | P28566 | 3/20 | 0.59 |
| ▸ | HTR1F | P30939 | 3/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6969852 | 0.99 | HTR6 (0.61) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL6977685 | 0.84 | HTR6 (0.63) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL6980951 | 0.79 | HTR6 (0.80) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL6975242 | 0.78 | HTR6 (0.72) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL14113985 | 0.76 | HTR6 (0.63) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL6975269 | 0.74 | HTR6 (0.86) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL1136525 | 0.74 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL29496144 | 0.74 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL3947243 | 0.73 | HTR6 (0.65) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| Hydrochloric Acid SCHEMBL7532427 | 0.73 | HTR6 (0.64) | HTR6HTR1AHTR1DHTR1BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946539-B1 | SULPHONAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-13 | — | — | EP | claimed |