Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985562 | 0.83 | NR3C1 (0.56) | NR3C1BRD4CREBBPSMN1; SMN2ALDH1A1 | |
| SCHEMBL6987762 | 0.80 | BRD4 (0.48) | NR3C1BRD4CREBBPSMN1; SMN2MAPT | |
| SCHEMBL6982938 | 0.80 | NR3C1 (0.51) | NR3C1BRD4CREBBPSMN1; SMN2MAPT | |
| SCHEMBL6987626 | 0.79 | NR3C1 (0.64) | NR3C1BRD4CREBBPSMN1; SMN2ALDH1A1 | |
| SCHEMBL6984139 | 0.78 | NR3C1 (0.50) | NR3C1BRD4CREBBPSMN1; SMN2MAPT | |
| SCHEMBL6981289 | 0.78 | NR3C1 (0.49) | NR3C1SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL6977731 | 0.77 | TP53 (0.45) | BRD4CREBBPSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6977631 | 0.77 | BRD4 (0.56) | NR3C1BRD4CREBBPSMN1; SMN2MAPT | |
| SCHEMBL6984100 | 0.77 | TP53 (0.41) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL6985317 | 0.77 | NR3C1 (0.58) | NR3C1SMN1; SMN2MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |