Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7657525 | 0.98 | PSEN1 (0.32) | PSEN1 | |
| SCHEMBL7090883 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL10084011 | 0.73 | PTGS1 (0.41) | — | |
| SCHEMBL19914863 | 0.71 | PSEN1 (0.38) | PSEN1 | |
| SCHEMBL20032244 | 0.68 | PSEN1 (0.48) | PSEN1 | |
| SCHEMBL10083807 | 0.65 | PGR (0.30) | — | |
| SCHEMBL10074179 | 0.64 | PSEN1 (0.52) | PSEN1 | |
| SCHEMBL7140905 | 0.64 | KDM4E (0.30) | — | |
| SCHEMBL16575414 | 0.62 | NQO1 (0.40) | — | |
| SCHEMBL7085788 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995743-B1 | Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans | SERVIER LAB (FR) | 2003-04-02 | — | — | EP | claimed |
| US-6350759-B1 | ANTIOXIDATIVE AGENTS FOR OXIDATION STRESS, ESPECIALLY AT THE CEREBRAL LEVEL; | ADIR ET COMPAGNIE (FR) | 2002-02-26 | — | — | US | claimed |
| EP-0995743-A1 | Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans | ADIR ET COMPAGNIE (FR) | 2000-04-26 | — | — | EP | claimed |
| EP-0995743-B1 | Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans | SERVIER LAB (FR) | 2003-04-02 | — | — | EP | disclosed |
| US-6350759-B1 | ANTIOXIDATIVE AGENTS FOR OXIDATION STRESS, ESPECIALLY AT THE CEREBRAL LEVEL; | ADIR ET COMPAGNIE (FR) | 2002-02-26 | — | — | US | disclosed |
| EP-0995743-A1 | Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans | ADIR ET COMPAGNIE (FR) | 2000-04-26 | — | — | EP | disclosed |