Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 20/20 | 1.00 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390814 | 0.90 | ITGB3 (0.82) | ITGB3ITGA2B | |
| SCHEMBL7391723 | 0.89 | ITGB3 (0.79) | ITGB3ITGA2BITGAV | |
| SCHEMBL7178442 | 0.88 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL9389691 | 0.87 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7385792 | 0.87 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL6984596 | 0.87 | ITGB3 (0.76) | ITGB3ITGA2B | |
| SCHEMBL9389702 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL9390820 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL7384974 | 0.84 | ITGB3 (0.79) | ITGB3ITGA2B | |
| SCHEMBL9390830 | 0.84 | ITGB3 (0.72) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | claimed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | claimed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | claimed |
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |