Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15897866 | 0.92 | CRBN (0.55) | KDM4EMAPTPKMHPGDPHGDH | |
| SCHEMBL6982244 | 0.88 | KDM4E (0.64) | KDM4EMAPTHPGDCRBNALDH1A1 | |
| SCHEMBL30031951 | 0.86 | MAPT (0.58) | KDM4EMAPTHPGDCRBNALDH1A1 | |
| SCHEMBL6976973 | 0.82 | KDM4E (0.57) | KDM4EMAPTHPGDCRBNALDH1A1 | |
| SCHEMBL30226880 | 0.82 | CRBN (0.58) | KDM4EMAPTHPGDCRBNALDH1A1 | |
| SCHEMBL15898298 | 0.81 | CRBN (0.55) | KDM4EPKMHPGDPHGDHCRBN | |
| SCHEMBL22226394 | 0.81 | CRBN (0.57) | KDM4EMAPTHPGDCRBNALDH1A1 | |
| SCHEMBL30226900 | 0.81 | CRBN (0.57) | KDM4EMAPTHPGDCRBNALDH1A1 | |
| SCHEMBL7325238 | 0.79 | CRBN (0.58) | PKMHPGDPHGDHCRBNHSP90AA1 | |
| SCHEMBL6980782 | 0.77 | KDM4E (0.60) | KDM4EMAPTHPGDCRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |