Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031951 | 0.89 | MAPT (0.58) | KDM4EMAPTHPGDALDH1A1ACHE | |
| SCHEMBL6982244 | 0.85 | KDM4E (0.64) | KDM4EMAPTHPGDALDH1A1NPC1 | |
| SCHEMBL6980782 | 0.85 | KDM4E (0.60) | KDM4EMAPTHPGDALDH1A1ACHE | |
| SCHEMBL6978588 | 0.82 | KDM4E (0.59) | KDM4EMAPTHPGDALDH1A1MASP2 | |
| SCHEMBL15880405 | 0.81 | CRBN (0.54) | KDM4EMAPTALDH1A1ACHECRBN | |
| SCHEMBL11042646 | 0.80 | CRBN (0.60) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL30226880 | 0.80 | CRBN (0.58) | KDM4EMAPTHPGDALDH1A1TSHR | |
| SCHEMBL22226793 | 0.79 | PDK1 (0.47) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL22226394 | 0.79 | CRBN (0.57) | KDM4EMAPTHPGDALDH1A1NPC1 | |
| SCHEMBL30226900 | 0.79 | CRBN (0.57) | KDM4EMAPTHPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |