Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 12/20 | 0.78 |
| ▸ | RAB9A | P51151 | 11/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | CASP3 | P42574 | 1/20 | 0.74 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.74 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.74 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.69 |
| ▸ | PLAU | P00749 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429748 | 1.00 | PABPC1 (1.00) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL4434499 | 0.92 | PABPC1 (0.85) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL29647732 | 0.89 | PABPC1 (0.80) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL19631378 | 0.89 | PABPC1 (0.80) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL14082279 | 0.88 | PABPC1 (0.79) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7101847 | 0.88 | PABPC1 (0.79) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL1681688 | 0.86 | PABPC1 (0.75) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL14462125 | 0.86 | PABPC1 (0.74) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL19631311 | 0.85 | NPC1 (0.80) | PABPC1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL19663016 | 0.85 | PABPC1 (0.74) | PABPC1NPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |