Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.54 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673273 | 0.84 | TDP1 (0.66) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL1249053 | 0.82 | GSK3B (0.73) | CSNK2A1DYRK1AAKR1B1TDP1GSK3B | |
| SCHEMBL1249051 | 0.82 | GSK3B (0.73) | CSNK2A1DYRK1AAKR1B1TDP1GSK3B | |
| SCHEMBL7510151 | 0.73 | CSNK2A2 (0.45) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL6785387 | 0.73 | IGF1R (0.67) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL9254370 | 0.72 | PIM1 (0.71) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL7463867 | 0.72 | PIM1 (0.68) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL4156417 | 0.72 | CSNK2A2 (0.65) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL7519991 | 0.72 | CSNK2A2 (0.65) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL9376844 | 0.71 | PTPN1 (0.72) | CSNK2A1DYRK1ACSNK2A2CLK1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186588-A1 | 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-03-13 | — | — | EP | claimed |
| JP-10139768-A | — | — | None | — | — | JP | disclosed |
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| EP-1186588-A1 | 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |
| JP-H10139768-A | PRODUCTION OF NAPHTHALENE DERIVATIVE | MITSUBISHI CHEM CORP | 1998-05-26 | — | — | JP | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |