Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976784 | 0.84 | POLB (0.52) | ITGB3ITGA2BGAAMAPTPOLB | |
| SCHEMBL6976581 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BGAAMAPTNAMPT | |
| SCHEMBL7345363 | 0.80 | ITGB3 (0.55) | ITGB3ITGA2BGAAMAPTTSHR | |
| SCHEMBL7347870 | 0.79 | ITGB3 (0.57) | ITGB3ITGA2BGAAMAPT | |
| SCHEMBL7348941 | 0.79 | ITGB3 (0.57) | ITGB3ITGA2BGAAMAPT | |
| SCHEMBL7421564 | 0.78 | ITGB3 (0.50) | ITGB3ITGA2BGAAMAPTTSHR | |
| SCHEMBL7353542 | 0.72 | ITGB3 (0.69) | ITGB3ITGA2BGAAMAPTF2 | |
| SCHEMBL6980649 | 0.71 | ADORA2A (0.41) | ITGB3ITGA2BGAAMAPTNAMPT | |
| SCHEMBL13714942 | 0.71 | ITGB3 (0.70) | ITGB3ITGA2BF2 | |
| SCHEMBL6978828 | 0.71 | ITGB3 (0.48) | ITGB3ITGA2BGAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |