Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.69 |
| ▸ | HTR1D | P28221 | 4/20 | 0.68 |
| ▸ | HTR2C | P28335 | 5/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.65 |
| ▸ | HTR1A | P08908 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | HTR1B | P28222 | 2/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.65 |
| ▸ | HTR3B | O95264 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | HTR1E | P28566 | 1/20 | 0.65 |
| ▸ | HTR1F | P30939 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980070 | 0.98 | SLC6A4 (0.68) | SLC6A4HTR1DHTR2CTRPV1HTR1A | |
| SCHEMBL6987521 | 0.95 | SLC6A4 (0.71) | SLC6A4HTR1DHTR2CTRPV1HTR1A | |
| SCHEMBL7002494 | 0.92 | HTR2C (0.77) | SLC6A4HTR1DHTR2CHTR1AHTR2A | |
| SCHEMBL6986225 | 0.89 | HTR1D (0.73) | SLC6A4HTR1DHTR2CTRPV1HTR1A | |
| SCHEMBL453066 | 0.86 | TRPV1 (0.67) | HTR1DHTR2CTRPV1HTR1ACYP2D6 | |
| SCHEMBL23630278 | 0.85 | TRPV1 (0.69) | HTR1DHTR2CTRPV1HTR1ACYP2D6 | |
| SCHEMBL23633204 | 0.85 | TRPV1 (0.69) | HTR1DHTR2CTRPV1HTR1ACYP2D6 | |
| SCHEMBL25076891 | 0.85 | TRPV1 (0.69) | HTR1DHTR2CTRPV1HTR1ACYP2D6 | |
| SCHEMBL25076884 | 0.85 | TRPV1 (0.69) | HTR1DHTR2CTRPV1HTR1ACYP2D6 | |
| SCHEMBL25076703 | 0.85 | TRPV1 (0.69) | HTR1DHTR2CTRPV1HTR1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5230020-A | — | — | None | — | — | JP | disclosed |
| EP-1268422-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | Bayer Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070687-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-27 | — | — | WO | disclosed |
| JP-H05230020-A | 3-ARYL-5-HYDROXYINDOLE DERIVATIVE AND ITS PRODUCTION | FUJI PHOTO FILM CO LTD | 1993-09-07 | — | — | JP | disclosed |