Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.62 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877349 | 0.83 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL16097011 | 0.82 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3TACR1GBA1 | |
| Hydrochloric Acid SCHEMBL5235119 | 0.79 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TACR1GBA1 | |
| SCHEMBL8311787 | 0.78 | KMT2A (0.55) | — | |
| SCHEMBL5428676 | 0.77 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL16757328 | 0.77 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3TACR1 | |
| SCHEMBL5994946 | 0.77 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5234528 | 0.76 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL5993834 | 0.75 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL24424448 | 0.73 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |