Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978433 | 0.86 | MEN1 (0.53) | KMT2AMEN1ALDH1A1CCR5RAB9A | |
| SCHEMBL29243353 | 0.80 | MEN1 (0.50) | KMT2AMEN1ALDH1A1CCR5RAB9A | |
| SCHEMBL6978832 | 0.78 | SLC6A2 (0.62) | — | |
| SCHEMBL28404291 | 0.75 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1CCR5RAB9A | |
| SCHEMBL16757240 | 0.74 | KMT2A (0.69) | KMT2AMEN1ALDH1A1CCR5RAB9A | |
| SCHEMBL785972 | 0.74 | JAK2 (0.54) | KMT2AMEN1ALDH1A1OPRM1CHRM2 | |
| SCHEMBL16757186 | 0.73 | KMT2A (0.65) | KMT2AMEN1ALDH1A1CCR5RAB9A | |
| SCHEMBL20959482 | 0.73 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1CCR5 | |
| SCHEMBL16321987 | 0.72 | KMT2A (0.50) | KMT2AMEN1ALDH1A1CCR5 | |
| SCHEMBL8311276 | 0.72 | SOS1 (0.58) | KMT2AMEN1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |