Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086609 | 1.00 | IDO1 (0.31) | IDO1ABCB1LMNAKCNE1KCNQ1 | |
| SCHEMBL13358844 | 1.00 | IDO1 (0.31) | IDO1ABCB1LMNAKCNE1KCNQ1 | |
| SCHEMBL4848406 | 0.81 | HTR2A (0.32) | — | |
| SCHEMBL4020277 | 0.81 | HTR2A (0.32) | — | |
| SCHEMBL2471392 | 0.78 | ABCB1 (0.42) | ABCB1 | |
| SCHEMBL2473015 | 0.77 | AKR1B1 (0.37) | LMNA | |
| SCHEMBL6985601 | 0.77 | AKR1B1 (0.37) | LMNA | |
| SCHEMBL2475336 | 0.77 | AKR1B1 (0.37) | LMNA | |
| SCHEMBL2471965 | 0.77 | AKR1B1 (0.37) | LMNA | |
| SCHEMBL7684277 | 0.77 | AKR1B1 (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229371-C | Benzopyran guanidine derivatives, process for preparing the same, and pharmaceutical composition thereof | KOREA RES INST CHEM TECH (KR) | 2005-11-30 | — | — | CN | disclosed |
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| CN-1382134-A | Benzopyranyl guanidine derivtives, process for preparation thereof and pharmaceutical compositions containing them | KOREA RES INST CHEM TECH (KR) | 2002-11-27 | — | — | CN | disclosed |
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |