Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983532 | 0.98 | CDK1 (0.55) | CDK1MEN1KMT2ASMN1; SMN2KIF11 | |
| SCHEMBL9453957 | 0.82 | CDK1 (0.68) | CDK1MEN1KMT2ASMN1; SMN2KIF11 | |
| SCHEMBL6986153 | 0.81 | MAPT (0.68) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL8983504 | 0.80 | MAPT (0.69) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL8983416 | 0.79 | GAA (0.58) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL6986158 | 0.78 | MAPT (0.68) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL6982146 | 0.77 | MAPT (0.56) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL6977163 | 0.77 | KMT2A (0.55) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL17956747 | 0.75 | KMT2A (0.69) | CDK1MEN1KMT2ASMN1; SMN2KIF11 | |
| SCHEMBL2973297 | 0.75 | MAPT (0.58) | SMN1; SMN2LMNAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |