Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 5/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | XBP1 | P17861 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983504 | 0.98 | MAPT (0.69) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL6986153 | 0.97 | MAPT (0.68) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL7175227 | 0.84 | MAPT (0.86) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL4679918 | 0.81 | MAPT (0.53) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL22567938 | 0.80 | MAPT (0.78) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL8983532 | 0.80 | CDK1 (0.55) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL22567749 | 0.80 | MAPT (0.78) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL4685324 | 0.78 | IDO1 (0.63) | MAPTALDH1A1GAANPSR1IDO1 | |
| SCHEMBL12412637 | 0.78 | ALDH1A1 (0.76) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL6979193 | 0.78 | CDK1 (0.54) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |