Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978907 | 0.92 | PTGS2 (0.57) | PTGS2PTGS1HSD11B1 | |
| SCHEMBL6979031 | 0.88 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL6981954 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL6978726 | 0.84 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL6982238 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6979325 | 0.83 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6977368 | 0.82 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL6970812 | 0.82 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6976650 | 0.81 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL6977248 | 0.81 | PTGS2 (0.81) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | claimed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | claimed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | claimed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | claimed |
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | disclosed |