Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.52 |
| ▸ | FNTB | P49356 | 17/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984623 | 0.92 | FNTA (0.56) | FNTAFNTBCNR2MEN1MAPT | |
| SCHEMBL6971909 | 0.88 | FNTA (0.52) | FNTAFNTBCNR2CYP3A4PGGT1B | |
| SCHEMBL6982646 | 0.88 | FNTA (0.67) | FNTAFNTBCNR2CYP3A4PGGT1B | |
| SCHEMBL6982725 | 0.87 | FNTA (0.68) | FNTAFNTBCNR2MAPTHTT | |
| SCHEMBL6975762 | 0.87 | FNTA (0.66) | FNTAFNTBCNR2CYP3A4PGGT1B | |
| SCHEMBL6976044 | 0.86 | FNTA (0.56) | FNTAFNTBCNR2CYP3A4PGGT1B | |
| SCHEMBL6925142 | 0.86 | FNTA (0.53) | FNTAFNTBMEN1KMT2AMCL1 | |
| SCHEMBL6980460 | 0.84 | FNTA (0.67) | FNTAFNTBMEN1KMT2ATDP1 | |
| SCHEMBL6976425 | 0.83 | FNTA (0.56) | FNTAFNTBCNR2 | |
| SCHEMBL6978528 | 0.83 | FNTA (0.56) | FNTAFNTBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6268363-B1 | ANTITUMOR | LG CHEMICAL LTD. (KR) | 2001-07-31 | — | — | US | claimed |