Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.67 |
| ▸ | FNTB | P49356 | 11/20 | 0.67 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925142 | 0.86 | FNTA (0.53) | FNTAFNTBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6979313 | 0.84 | FNTA (0.52) | FNTAFNTBKMT2AMEN1TDP1 | |
| SCHEMBL6984623 | 0.84 | FNTA (0.56) | FNTAFNTBCDC25BKMT2AMEN1 | |
| SCHEMBL6982725 | 0.83 | FNTA (0.68) | FNTAFNTBALDH1A1 | |
| SCHEMBL6975762 | 0.83 | FNTA (0.66) | FNTAFNTB | |
| SCHEMBL27519189 | 0.82 | FNTA (0.56) | FNTAFNTBCDC25BCDC25ACDC25C | |
| SCHEMBL6976044 | 0.82 | FNTA (0.56) | FNTAFNTBKMT2AALDH1A1 | |
| SCHEMBL6976566 | 0.81 | FNTA (0.57) | FNTAFNTBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6977393 | 0.81 | FNTA (0.57) | FNTAFNTBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6976451 | 0.80 | FNTA (0.50) | FNTAFNTBKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |
| US-6268363-B1 | ANTITUMOR | LG CHEMICAL LTD. (KR) | 2001-07-31 | — | — | US | disclosed |
| EP-1045846-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028315-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1999-06-10 | — | — | WO | disclosed |