Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666833 | 0.87 | GPR119 (0.53) | POLBGPR119KDM4EPKMFAAH | |
| SCHEMBL6984087 | 0.83 | GPR119 (0.51) | POLBGPR119SYKKDM4EPKM | |
| SCHEMBL18228507 | 0.80 | GPR119 (0.53) | POLBGPR119KDM4EPKMFAAH | |
| SCHEMBL31678664 | 0.79 | PARP1 (0.46) | SYKKDM4EPARP1 | |
| SCHEMBL22583344 | 0.79 | PARP1 (0.46) | SYKKDM4EPARP1 | |
| SCHEMBL1088570 | 0.78 | GPR119 (0.61) | POLBGPR119KDM4EPKMFAAH | |
| SCHEMBL29566603 | 0.78 | GPR119 (0.61) | POLBGPR119KDM4EPKMFAAH | |
| SCHEMBL20281797 | 0.78 | ALOX5AP (0.53) | POLBGPR119KDM4EPKMFAAH | |
| SCHEMBL21607904 | 0.78 | ALOX5AP (0.53) | POLBGPR119KDM4EPKMFAAH | |
| SCHEMBL7710611 | 0.78 | PTPN2 (0.57) | POLBGPR119PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839145-B1 | HETEROCYCLYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO KG (DE) | 2003-11-05 | — | — | EP | disclosed |