Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979078 | 0.77 | POLB (0.42) | HRH3 | |
| SCHEMBL7957882 | 0.73 | CYP1A2 (0.44) | GNAO1GBA1HRH3 | |
| SCHEMBL332080 | 0.72 | GNAO1 (0.45) | GNAO1GBA1HRH3 | |
| Hydrochloric Acid SCHEMBL8902556 | 0.71 | GNAO1 (0.41) | GNAO1HRH3 | |
| Hydrochloric Acid SCHEMBL11196770 | 0.71 | GNAO1 (0.43) | GNAO1GBA1HRH3 | |
| SCHEMBL6980801 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL3670602 | 0.70 | GNAO1 (0.48) | GNAO1GBA1HRH3 | |
| SCHEMBL9384345 | 0.70 | GNAO1 (0.44) | GNAO1GBA1HRH3 | |
| Hydrochloric Acid SCHEMBL4486629 | 0.70 | GNAO1 (0.48) | GNAO1GBA1HRH3 | |
| SCHEMBL6969276 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |