Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.70 |
| ▸ | MAOB | P27338 | 5/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | SDHA | P31040 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CALML3 | P27482 | 1/20 | 0.70 |
| ▸ | F10 | P00742 | 8/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979714 | 1.00 | MAOA (0.70) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8575816 | 0.89 | MAOA (0.71) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8575809 | 0.89 | MAOA (0.71) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8578671 | 0.87 | MAOA (0.71) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8578679 | 0.87 | MAOA (0.71) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8578539 | 0.86 | MAOA (0.70) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8308534 | 0.86 | MAOA (0.70) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8311659 | 0.86 | MAOA (0.70) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8575489 | 0.86 | MAOA (0.70) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6984842 | 0.86 | MAOB (0.75) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868424-B1 | 4-PYRIMIDINYL- OR 4-PYRAZINYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTI-BACTERIAL AGENTS | UPJOHN CO (US) | 2003-02-12 | — | — | EP | claimed |
| EP-0868424-B1 | 4-PYRIMIDINYL- OR 4-PYRAZINYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTI-BACTERIAL AGENTS | UPJOHN CO (US) | 2003-02-12 | — | — | EP | disclosed |