⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817819 | 0.79 | CYP19A1 (0.35) | — | |
| SCHEMBL9488314 | 0.79 | CYP19A1 (0.35) | — | |
| SCHEMBL9514183 | 0.78 | — | — | |
| SCHEMBL104541 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL8863481 | 0.74 | CYP19A1 (0.39) | — | |
| SCHEMBL23119198 | 0.72 | CYP19A1 (0.38) | — | |
| SCHEMBL13863261 | 0.72 | — | — | |
| SCHEMBL8657854 | 0.72 | — | — | |
| SCHEMBL24683919 | 0.72 | — | — | |
| SCHEMBL4313822 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563655-A | Preparation method of 5- (2-bromoethyl) pyrimidine | 上海毕得医药科技有限公司 | 2019-12-13 | — | — | CN | claimed |
| US-11731944-B2 | SARS-CoV-2 inhibitors for treating coronavirus infections | INSILICO MEDICINE IP LIMITED (HK) | 2023-08-22 | — | — | US | disclosed |
| US-20230192624-A1 | SARS-COV-2 INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
| US-10947206-B2 | cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| CN-109134267-B | Synthetic method of aromatic amine compound | 北京大学 | 2020-11-17 | — | — | CN | disclosed |
| CN-110563655-A | Preparation method of 5- (2-bromoethyl) pyrimidine | 上海毕得医药科技有限公司 | 2019-12-13 | — | — | CN | disclosed |
| US-10197930-B2 | Electrophotographic member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2019-02-05 | — | — | US | disclosed |
| EP-3275870-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | Gilead Sciences, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| US-20170060007-A1 | ELECTROPHOTOGRAPHIC MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2017-03-02 | — | — | US | disclosed |
| CN-103739556-A | Preparation method and detection method of 2,4-dibromopyrimidine | UNIV HEBEI SCIENCE & TECH | 2014-04-23 | — | — | CN | disclosed |
| CN-102295635-B | Antitumor medicament tetralin amide compounds and pharmaceutically acceptable salts thereof as well as preparation method and application of antitumor medicament tetralin amide compounds | UNIV LIAONING | 2013-10-09 | — | — | CN | disclosed |
| CN-102295635-A | Antitumor medicament tetralin amide compounds and pharmaceutically acceptable salts thereof as well as preparation method and application of antitumor medicament tetralin amide compounds | — | 2011-12-28 | — | — | CN | disclosed |
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-6018046-A | SELECTIVE ACTION IN INHIBITING CYCLIC GMP-PHOSPHODIESTERASE (CGMP-PDE); PHARMACEUTICALS FOR TREATING DISEASES AGAINST WHICH THE INHIBITORY ACTION IS EFFECTIVE, SUCH AS PULMONARY HYPERTENSION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |