⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63173 | 0.77 | — | — | |
| SCHEMBL150818 | 0.77 | — | — | |
| SCHEMBL28581942 | 0.74 | IDO1 (0.38) | — | |
| Benzene SCHEMBL10711738 | 0.74 | IDO1 (0.38) | — | |
| SCHEMBL9673849 | 0.71 | IDO1 (0.42) | — | |
| Hydrazine SCHEMBL11860025 | 0.71 | CYP3A4 (0.37) | — | |
| SCHEMBL1408877 | 0.70 | — | — | |
| SCHEMBL29769303 | 0.69 | IDO1 (0.50) | — | |
| SCHEMBL27090229 | 0.69 | IDO1 (0.50) | — | |
| SCHEMBL316960 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110785418-A | Isoindolinone derivatives as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2020-02-11 | — | — | CN | disclosed |
| CN-110770229-A | Benzofuran compounds as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2020-02-07 | — | — | CN | disclosed |
| CN-101687944-B | Polar group-containing polyolefin polymer, process for producing the same, aqueous dispersion, and mold release agent composition | MITSU CHEMICALS INC | 2012-07-25 | — | — | CN | disclosed |
| CN-101687944-A | Polar group-containing polyolefin polymer, process for producing the same, aqueous dispersion, and mold release agent composition | MITSUI CHEMICALS INC | 2010-03-31 | — | — | CN | disclosed |
| CN-100537573-C | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | TORAY INDUSTRIES (JP) | 2009-09-09 | — | — | CN | disclosed |
| CN-1703415-A | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | TORAY INDUSTRIES (JP) | 2005-11-30 | — | — | CN | disclosed |
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| CN-1284075-A | Novel compounds having CGMP-PDE inhibitory effect | MOCHIDA PHARM CO LTD (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-6018046-A | SELECTIVE ACTION IN INHIBITING CYCLIC GMP-PHOSPHODIESTERASE (CGMP-PDE); PHARMACEUTICALS FOR TREATING DISEASES AGAINST WHICH THE INHIBITORY ACTION IS EFFECTIVE, SUCH AS PULMONARY HYPERTENSION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| WO-1998030572-A1 | PROCESSES FOR THE PREPARATION OF αGal(1→4)βGal(1→4)Glc-OR | SYNSORB BIOTECH, INC. (CA) | 1998-07-16 | — | — | WO | disclosed |