Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977885 | 0.91 | NR3C1 (0.48) | NR3C1BRD4CREBBPSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6979711 | 0.88 | F2 (0.54) | ROCK2NR3C1BRD4CREBBPPKLR | |
| SCHEMBL6977631 | 0.83 | BRD4 (0.56) | NR3C1BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL6977179 | 0.83 | NR3C1 (0.64) | NR3C1BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL6982493 | 0.82 | NR3C1 (0.50) | NR3C1BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL7960284 | 0.82 | NR3C1 (0.47) | NR3C1BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL6985317 | 0.81 | NR3C1 (0.58) | NR3C1SMN1; SMN2 | |
| SCHEMBL6982160 | 0.81 | NR3C1 (0.61) | NR3C1SMN1; SMN2 | |
| SCHEMBL6977969 | 0.79 | NR3C1 (0.56) | NR3C1SMN1; SMN2 | |
| SCHEMBL6978212 | 0.79 | TRIM24 (0.48) | NR3C1BRD4CREBBPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |