Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.61 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980989 | 1.00 | F10 (0.61) | F10PRSS1KCNA5GPR119ALOX5AP | |
| SCHEMBL6981523 | 0.85 | F10 (0.61) | F10PRSS1 | |
| SCHEMBL6981524 | 0.85 | F10 (0.61) | F10PRSS1 | |
| SCHEMBL6985486 | 0.83 | F10 (0.51) | F10PRSS1 | |
| SCHEMBL6985483 | 0.83 | F10 (0.51) | F10PRSS1 | |
| SCHEMBL6985479 | 0.83 | F10 (0.51) | F10PRSS1 | |
| SCHEMBL6986095 | 0.80 | F10 (0.49) | F10PRSS1 | |
| SCHEMBL6986091 | 0.80 | F10 (0.49) | F10PRSS1 | |
| SCHEMBL6986090 | 0.80 | F10 (0.49) | F10PRSS1 | |
| SCHEMBL6980029 | 0.79 | F10 (0.57) | F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934265-B1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6057342-A | INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASE ENZYMES, ESPECIALLY FACTOR XA, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME AS ANTICOAGULANT AGENTS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISORDERS | DUPONT PHARMACEUTICAL CO. (US) | 2000-05-02 | — | — | US | disclosed |