Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981524 | 1.00 | F10 (0.61) | F10PRSS1 | |
| SCHEMBL6980029 | 0.92 | F10 (0.57) | F10PRSS1 | |
| SCHEMBL6984372 | 0.90 | F10 (0.75) | F10PRSS1 | |
| SCHEMBL6984366 | 0.90 | F10 (0.75) | F10PRSS1 | |
| SCHEMBL6980989 | 0.85 | F10 (0.61) | F10PRSS1 | |
| SCHEMBL6980992 | 0.85 | F10 (0.61) | F10PRSS1 | |
| SCHEMBL6984364 | 0.85 | F10 (0.43) | F10PRSS1 | |
| SCHEMBL6984369 | 0.85 | F10 (0.43) | F10PRSS1 | |
| SCHEMBL6986034 | 0.82 | F10 (0.51) | F10PRSS1 | |
| SCHEMBL6986028 | 0.82 | F10 (0.51) | F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934265-B1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6057342-A | INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASE ENZYMES, ESPECIALLY FACTOR XA, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME AS ANTICOAGULANT AGENTS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISORDERS | DUPONT PHARMACEUTICAL CO. (US) | 2000-05-02 | — | — | US | disclosed |