Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2749806 | 0.89 | TSHR (0.64) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1996019 | 0.86 | TSHR (0.60) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2749808 | 0.86 | TSHR (0.60) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8442593 | 0.81 | TXNRD1 (0.68) | TSHRMAPTALDH1A1LMNATXNRD1 | |
| SCHEMBL7597811 | 0.80 | TSHR (0.62) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19759816 | 0.76 | MAPK1 (0.56) | TSHRCYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL282648 | 0.76 | TSHR (0.56) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2959825 | 0.76 | MAPT (0.71) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2963606 | 0.76 | MAPT (0.55) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21445768 | 0.75 | TSHR (0.55) | TSHRCYP3A4SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296967-A1 | QUINOLINYL AND BENZOTHIAZOLYL PPAR-GAMMA MODULATORS | Tularik Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002000633-A1 | QUINOLINYL AND BENZOTHIAZOLYL PPAR-GAMMA MODULATORS | TULARIK INC. (US) | 2002-01-03 | — | — | WO | disclosed |