Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958167 | 0.70 | CYP2A6 (0.31) | — | |
| SCHEMBL28029640 | 0.69 | — | — | |
| SCHEMBL6009919 | 0.67 | — | — | |
| SCHEMBL29048569 | 0.66 | — | — | |
| SCHEMBL28658397 | 0.62 | HDAC1 (0.33) | ALDH1A1 | |
| SCHEMBL4939750 | 0.61 | NPC1 (0.33) | ALDH1A1 | |
| SCHEMBL10468311 | 0.61 | PTGS1 (0.34) | PTGS2PTGS1ALPLALDH1A1 | |
| SCHEMBL30163529 | 0.61 | NPC1 (0.32) | ALDH1A1 | |
| SCHEMBL28540735 | 0.61 | NPC1 (0.32) | ALDH1A1 | |
| SCHEMBL28513177 | 0.61 | NPC1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244446-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1244446-A1 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001039773-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |