Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19181986 | 0.84 | NPC1 (0.33) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL29283410 | 0.79 | HDAC4 (0.31) | NPC1RAB9A | |
| SCHEMBL8957775 | 0.78 | HDAC1 (0.37) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL28513177 | 0.78 | NPC1 (0.32) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL30163529 | 0.78 | NPC1 (0.32) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL28540735 | 0.78 | NPC1 (0.32) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL27711885 | 0.78 | — | — | |
| Methane SCHEMBL28875106 | 0.77 | HDAC1 (0.36) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL9006818 | 0.76 | THRB (0.35) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL27691809 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835680-B | Novel selective 11-beta-hydroxysteroid dehydrogenase type 1 | 帝斯曼知识产权资产管理有限公司 | 2021-11-09 | — | — | CN | disclosed |