Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151902 | 0.87 | SMO (0.40) | HSP90AA1HSP90B1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL7189934 | 0.86 | HSP90AA1 (0.42) | HSP90AA1HSP90B1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL4978567 | 0.85 | HSP90AA1 (0.41) | HSP90AA1HSP90B1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL1507873 | 0.84 | CYP11B1 (0.48) | HSP90AA1HSP90B1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL30610947 | 0.84 | CYP11B1 (0.48) | HSP90AA1HSP90B1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL1508003 | 0.84 | CYP19A1 (0.50) | HSP90AA1HSP90B1KMT2ACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL1507947 | 0.83 | CYP11B1 (0.47) | HSP90AA1HSP90B1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL446009 | 0.79 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1508007 | 0.78 | HSP90AA1 (0.50) | HSP90AA1HSP90B1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8149819 | 0.78 | HSP90AA1 (0.38) | HSP90AA1HSP90B1CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235826-A1 | Tyrosine kinase ihnibitors | MERCK SHARP & DOHME CORP. | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235826-A1 | Tyrosine kinase ihnibitors | KDR, FLT4, ERBB2 | HSP90AA1 706/4885HSP90B1 1085/4885KMT2A 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.