Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981562 | 1.00 | DRD2 (0.43) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| SCHEMBL7811043 | 1.00 | DRD2 (0.43) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| Bromide SCHEMBL7811677 | 0.99 | DRD2 (0.42) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| Bromide SCHEMBL7811682 | 0.99 | DRD2 (0.42) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| Hydrochloric Acid SCHEMBL6985847 | 0.99 | DRD2 (0.42) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| Hydrochloric Acid SCHEMBL6984757 | 0.99 | DRD2 (0.42) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| Hydrochloric Acid SCHEMBL7811763 | 0.99 | DRD2 (0.42) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| SCHEMBL7809132 | 0.93 | DRD2 (0.38) | DRD2SLC18A3CARM1PRMT6HTR7 | |
| Fumaric Acid SCHEMBL7802740 | 0.92 | SLC18A3 (0.37) | DRD2SLC18A3HTR7SIGMAR1MEN1 | |
| Fumaric Acid SCHEMBL7802738 | 0.92 | SLC18A3 (0.37) | DRD2SLC18A3HTR7SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | claimed |
| EP-0601547-B1 | Crystalline salts of optically active aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-09-12 | — | — | EP | claimed |
| US-5552552-A | ENZYME INHIBITORS FOR LIPIDPEROXIDASE FOR TREATMENT OF STROKE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-03 | — | — | US | claimed |
| US-5478844-A | Method of using aminocoumaran derivatives for treating cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | claimed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | claimed |
| US-5376681-A | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-27 | — | — | US | claimed |
| EP-0601547-A1 | Crystalline salts of optically active aminocoumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-06-15 | — | — | EP | claimed |
| JP-6228136-A | — | — | None | — | — | JP | disclosed |
| JP-9176157-A | — | — | None | — | — | JP | disclosed |
| EP-4627943-A1 | COMPOSITIONS AND METHODS | Nicoventures Trading Limited (GB) | 2025-10-08 | — | — | EP | disclosed |
| EP-4627939-A1 | METHODS | Nicoventures Trading Limited (GB) | 2025-10-08 | — | — | EP | disclosed |
| EP-4627940-A1 | COMPOSITIONS AND METHODS | Nicoventures Trading Limited (GB) | 2025-10-08 | — | — | EP | disclosed |
| EP-4627942-A1 | COMPOSITIONS AND METHODS | Nicoventures Trading Limited (GB) | 2025-10-08 | — | — | EP | disclosed |
| US-5478844-A | Method of using aminocoumaran derivatives for treating cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5376681-A | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| JP-H06228136-A | OPTICALLY ACTIVE AMINOCOUMARANE DERIVATIVE | TAKEDA CHEM IND LTD | 1994-08-16 | — | — | JP | disclosed |
| EP-0601547-A1 | Crystalline salts of optically active aminocoumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0601547-A1 | Crystalline salts of optically active aminocoumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0483772-A1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |