Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.37 |
| ▸ | CDK9 | P50750 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIPK1 | Q86Z02 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6977279 | 0.97 | CAMK2D (0.41) | CAMK2DPIM1CCNT1CDK9TDP1 | |
| Trifluoroacetic Acid SCHEMBL6982808 | 0.94 | CAMK2D (0.46) | CAMK2DPIM1CCNT1CDK9TDP1 | |
| Trifluoroacetic Acid SCHEMBL6977475 | 0.93 | CAMK2D (0.48) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL7672205 | 0.93 | CAMK2D (0.48) | CAMK2DPIM1CCNT1CDK9TDP1 | |
| Trifluoroacetic Acid SCHEMBL6978145 | 0.92 | CCNT1 (0.39) | CAMK2DPIM1CCNT1CDK9TDP1 | |
| Trifluoroacetic Acid SCHEMBL6979888 | 0.90 | PRKACA (0.41) | CAMK2DPIM1CCNT1CDK9TDP1 | |
| SCHEMBL7676681 | 0.90 | CAMK2D (0.47) | CAMK2DPIM1CCNT1CDK9TDP1 | |
| Trifluoroacetic Acid SCHEMBL6978585 | 0.88 | CCNT1 (0.40) | CAMK2DPIM1CCNT1CDK9TDP1 | |
| Trifluoroacetic Acid SCHEMBL6985258 | 0.87 | CAMK2D (0.39) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6975973 | 0.86 | CAMK2D (0.53) | CAMK2DPIM1CCNT1CDK9CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | disclosed |