Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.73 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5892593 | 0.90 | ADAMTS5 (0.67) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL5892537 | 0.88 | ADAMTS5 (0.79) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL5218002 | 0.88 | ADAMTS5 (0.73) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL2931055 | 0.88 | ADAMTS5 (0.70) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL2925494 | 0.87 | ADAMTS5 (0.69) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL186520 | 0.85 | ADAMTS5 (1.00) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL245003 | 0.85 | ADAMTS5 (1.00) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL5222372 | 0.85 | ADAMTS5 (0.77) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL2932473 | 0.84 | ADAMTS5 (0.67) | ADAMTS5AKR1B1PTPN1 | |
| SCHEMBL5215536 | 0.84 | ADAMTS5 (0.74) | ADAMTS5AKR1B1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313471-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | disclosed |