Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.62 |
| ▸ | FNTB | P49356 | 10/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.62 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983519 | 0.90 | FNTA (0.76) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6981647 | 0.83 | FNTA (0.69) | FNTAFNTBPGGT1BCNR2CYP11B1 | |
| SCHEMBL7080004 | 0.82 | FNTA (0.58) | FNTAFNTBPGGT1BCNR2CYP11B1 | |
| SCHEMBL6975814 | 0.82 | FNTA (0.76) | FNTAFNTBPGGT1BCNR2CYP11B1 | |
| SCHEMBL6983878 | 0.82 | FNTA (0.76) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6926980 | 0.80 | FNTA (0.73) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6983323 | 0.79 | FNTA (0.76) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6926512 | 0.78 | FNTA (0.72) | FNTAFNTBPGGT1BCNR2CYP3A4 | |
| SCHEMBL6983258 | 0.78 | FNTA (0.71) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982659 | 0.77 | FNTA (0.69) | FNTAFNTBPGGT1BCNR2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6268363-B1 | ANTITUMOR | LG CHEMICAL LTD. (KR) | 2001-07-31 | — | — | US | claimed |
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |
| US-6268363-B1 | ANTITUMOR | LG CHEMICAL LTD. (KR) | 2001-07-31 | — | — | US | disclosed |