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SCHEMBL6982147

SCHEMBL6982147

O=C(CN1C(=O)C(=Cc2ccc(OCc3cccc(C(F)(F)F)c3)c(OCc3ccccc3)c2)SC1=S)OC(=O)CN1C(=O)C(=Cc2ccc(OCc3ccc(F)cc3F)c(OCc3ccccc3)c2)SC1=S

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ADAMTS5 Q9UNA0 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6982141 0.95 ADAMTS5 (0.69) ADAMTS5
SCHEMBL5217802 0.88 ADAMTS5 (0.80) ADAMTS5
SCHEMBL5217797 0.88 ADAMTS5 (0.80) ADAMTS5
SCHEMBL5216729 0.87 ADAMTS5 (0.82) ADAMTS5
SCHEMBL5216733 0.87 ADAMTS5 (0.82) ADAMTS5
SCHEMBL6980129 0.86 ADAMTS5 (0.67) ADAMTS5
SCHEMBL14540543 0.85 ADAMTS5 (0.68) ADAMTS5
SCHEMBL5217584 0.83 ADAMTS5 (0.70) ADAMTS5
SCHEMBL5215486 0.83 ADAMTS5 (0.70) ADAMTS5
SCHEMBL5218570 0.81 ADAMTS5 (0.83) ADAMTS5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313471-A1 BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS Oxford GlycoSciences (UK) Limited (GB) 2003-05-28 — — EP disclosed
WO-2002017915-A1 BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS OXFORD GLYCOSCIENCES (UK) LIMITED (GB) 2002-03-07 — — WO disclosed