Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5674373 | 0.98 | CHRNA7 (0.55) | CHRNA7HTR3ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12615189 | 0.88 | POLB (0.60) | CHRNA7HTR3ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12614848 | 0.80 | CHRM3 (0.53) | CHRNA7HTR3AKDM4E | |
| SCHEMBL12614451 | 0.79 | KDM4E (0.54) | KDM4EPOLBCHRNA3 | |
| SCHEMBL4030570 | 0.76 | CHRNA7 (0.60) | CHRNA7HTR3ACHRNA3ACHE | |
| SCHEMBL3250162 | 0.74 | CHRNA7 (0.50) | CHRNA7NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2912984 | 0.73 | CHRNA7 (0.70) | CHRNA7HTR3ACHRNA3 | |
| SCHEMBL7559030 | 0.72 | CHRNA7 (1.00) | CHRNA7HTR3ACHRNA3 | |
| SCHEMBL31234028 | 0.72 | SMN1; SMN2 (0.67) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL4186674 | 0.72 | KMT2A (0.76) | NPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165559-B1 | 1,4-DIAZABICYCLO[3.2.2]NONANE-4-CARBOXYLATE AND CARBOXAMIDE DERIVATIVES, PRODUCTION AND USE THEREOF IN THERAPEUTICS | SANOFI SYNTHELABO (FR) | 2003-02-19 | — | — | EP | disclosed |