Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168367 | 0.85 | KMT2A (0.43) | ITGB3ITGA2BSIRT2SIRT1SIRT3 | |
| SCHEMBL5199197 | 0.82 | ACHE (0.44) | ALDH1A1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL5199193 | 0.82 | ACHE (0.44) | ALDH1A1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL12057564 | 0.82 | SIRT2 (0.45) | ITGB3ITGA2BSIRT2SIRT1SIRT3 | |
| SCHEMBL5198185 | 0.81 | ZDHHC7 (0.42) | ALDH1A1SIRT2SIRT1SIRT3TAS1R3 | |
| SCHEMBL12296373 | 0.81 | HDAC2 (0.48) | ALDH1A1SIRT2SIRT1SIRT3TAS1R3 | |
| SCHEMBL4778608 | 0.81 | CA1 (0.41) | ALDH1A1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL20683487 | 0.80 | CA1 (0.46) | ALDH1A1CA1CA2EPHX1ACHE | |
| SCHEMBL1696818 | 0.80 | CA1 (0.46) | ALDH1A1CA1CA2EPHX1ACHE | |
| Hydrochloric Acid SCHEMBL8872634 | 0.79 | CA1 (0.40) | ALDH1A1ITGB3ITGA2BSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358183-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| EP-1345931-A2 | CYSTEINE PROTEASE INHIBITORS | Medivir UK Ltd (GB) | 2003-09-24 | — | — | EP | disclosed |
| EP-1282594-A1 | BRANCHED AMINO ACIDS | Medivir UK Ltd (GB) | 2003-02-12 | — | — | EP | disclosed |
| WO-2002088106-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002040462-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LIMITED (GB) | 2002-05-23 | — | — | WO | disclosed |
| EP-1178986-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | Medivir UK Ltd (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2001087821-A1 | BRANCHED AMINO ACIDS | MEDIVIR UK LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |
| WO-2000069855-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LIMITED (GB) | 2000-11-23 | — | — | WO | disclosed |