Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27352909 | 0.88 | LMNA (0.40) | LMNAPDE4ATGFBR1 | |
| E968 SCHEMBL29468146 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL30337603 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL30033503 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL8127218 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL29624094 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL3479791 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL31043056 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL21625759 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 | |
| E968 SCHEMBL3621953 | 0.77 | LMNA (0.56) | LMNAPDE4AALOX15HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751161-B1 | Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin | MITSUI CHEMICALS INC (JP) | 2003-01-02 | — | — | EP | disclosed |
| CN-1082968-C | Sulfur-containing urethane-based resin composition, its resin, and optical element and lens comprising resin thereof | MITSUI CHEMICALS INC (JP) | 2002-04-17 | — | — | CN | disclosed |
| US-5736609-A | A POLYTHIO COMPOUND CONTAINING AT LEAST TWO MERCAPTO GROUPS, A POLYISO(THIO)CYANATE COMPOUND, AND A COMPOUND HAVING TWO OR MORE UNSATURATED REACTIVE GROUPS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-04-07 | — | — | US | disclosed |
| CN-1148055-A | Sulfur-containing urethane-based resin composition, its resin, and optical element and lens comprising resin thereof | MITSUI TOATSU CHEMICALS (JP) | 1997-04-23 | — | — | CN | disclosed |
| EP-0751161-A2 | Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-01-02 | — | — | EP | disclosed |