Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8156063 | 0.99 | ACHE (0.56) | ACHESMN1; SMN2KDM4EALDH1A1GPR139 | |
| SCHEMBL6984185 | 0.89 | SMN1; SMN2 (0.59) | ACHESMN1; SMN2KDM4EALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL8311791 | 0.88 | SMN1; SMN2 (0.58) | ACHESMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL6981531 | 0.87 | SMN1; SMN2 (0.48) | ACHESMN1; SMN2KDM4EALDH1A1GPR139 | |
| Hydrochloric Acid SCHEMBL8150064 | 0.86 | SMN1; SMN2 (0.47) | ACHESMN1; SMN2KDM4EALDH1A1GPR139 | |
| SCHEMBL6975566 | 0.86 | ACHE (0.58) | ACHESMN1; SMN2KDM4EALDH1A1GRM5 | |
| SCHEMBL6962160 | 0.84 | ACHE (0.55) | ACHESMN1; SMN2GRM5MAPK1MAPKAPK2 | |
| SCHEMBL6961470 | 0.84 | ACHE (0.57) | ACHESMN1; SMN2KDM4EALDH1A1GRM5 | |
| SCHEMBL6981511 | 0.84 | ACHE (0.57) | ACHEKDM4EALDH1A1GPR139NPC1 | |
| SCHEMBL6978218 | 0.84 | SMN1; SMN2 (0.58) | ACHESMN1; SMN2KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |