Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982329 | 1.00 | OPRK1 (0.53) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL6983247 | 0.92 | OPRK1 (0.52) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL6983250 | 0.92 | OPRK1 (0.52) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL6973674 | 0.90 | OPRK1 (0.61) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL6981228 | 0.90 | OPRK1 (0.61) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL6979508 | 0.90 | OPRK1 (0.61) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL6983978 | 0.90 | OPRK1 (0.61) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL6973676 | 0.90 | OPRK1 (0.61) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL8154488 | 0.90 | OPRK1 (0.59) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 | |
| SCHEMBL8154492 | 0.90 | OPRK1 (0.59) | OPRK1CYP2D6OPRM1OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| WO-1996030339-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1996-10-03 | — | — | WO | disclosed |